Oxycodone Addiction

Oxycodone addiction is a widespread issue touching lives all around the world, including right here in the UK. Falling into its grip is all too easy, yet breaking free is another battle. With access to effective treatment and support, those suffering from oxycodone addiction can successfully reclaim their lives, breaking free from the chains of addiction and embarking on a path toward recovery and wellness.

What is oxycodone?

Oxycodone is a semi-synthetic opioid synthesis from thebaine and one of the many alkaloids found in the opium poppy. Being semi-synthetic means that it is partially made through chemical synthesis based on natural opium-derived compounds. Oxycodone’s creation involves modifying thebaine’s chemical structure to achieve the desired therapeutic effects and potency.

Oxycodone can be prescribed for various conditions where pain relief is essential, such as after surgery, for cancer-related pain or for chronic conditions like arthritis. Because it is a potent opioid, it’s also associated with a risk of dependence and misuse, so it’s typically prescribed only when other pain management strategies are ineffective. Healthcare providers closely monitor its use to minimise these risks.

How does oxycodone work on the body?

Oxycodone works by binding to mu-opioid receptors in the brain and spinal cord, which are central nervous system (CNS) components. These receptors play a crucial role in how we perceive pain and reward mechanisms. Oxycodone’s activation of these receptors leads to a reduced perception of pain, essentially by modifying the emotional response to pain rather than directly targeting the physical source. This action makes the experience of pain more tolerable without altering the underlying cause.

Can you get addicted to oxycodone?

Yes, oxycodone has a high potential for addiction and dependency. A 2019 study and survey found that oxycodone was one of, if not the most, addictive prescription opioids available. The drug was consistently identified by participants in the study as the most desirable, most commonly recognised among associates as desirable, most addictive and, for a significant number, the gateway drug to heroin use.

The conclusion drawn from the study is clear: oxycodone’s risk of abuse and addiction significantly outweighs its benefits for long-term pain management. This finding suggests a need for cautious prescription practices and consideration of alternative pain management strategies to mitigate the risks associated with oxycodone use.

What factors make oxycodone addictive?

While many may associate oxycodone addiction with becoming accustomed to its euphoric and pain-relieving properties, there is actually a wide range of factors that contribute to its high potential for addiction.

Activation of the reward system

Oxycodone works by binding to opioid receptors in the brain, which can lead to a release of dopamine, a neurotransmitter associated with pleasure and reward. This dopamine release can reinforce the behaviour of taking the drug, leading to repeated use.

Tolerance development

With regular use, individuals may develop tolerance to oxycodone, meaning they require higher doses to achieve the same pain-relieving effects, which can lead to physical dependence.

Physical dependence

Over time, the body becomes accustomed to the presence of oxycodone, leading to physical dependence. When oxycodone use is reduced or stopped, oxycodone addiction symptoms can occur, encouraging continued use to avoid these unpleasant effects.

Psychological dependence

People may also develop a psychological dependence on oxycodone, relying on it to cope with stress, anxiety or other psychological issues, which can contribute to addiction.

Pain relief and euphoria

Oxycodone not only relieves pain but can also produce euphoria, especially when taken in amounts or by methods not prescribed (such as crushing and snorting or injecting), which can increase its addictive potential.

Accessibility and social factors

The availability of oxycodone, whether through prescriptions, from friends or family members or illicitly, can influence the risk of addiction.

What are the signs of oxycodone addiction?

Oxycodone addiction can affect a person’s entire life, including physical, psychological and behavioural changes:

Physical signs of oxycodone addiction

  • Tolerance: Needing an increasingly higher dose of oxycodone to achieve the same pain-relieving effects, leading to higher consumption over time.
  • Withdrawal symptoms: Experiencing withdrawal symptoms such as sweating, shaking, nausea, vomiting, diarrhoea and muscle aches when not taking the drug.
  • Changes in sleeping patterns: Experiencing insomnia or sleeping too much, disturbances in sleep patterns due to drug effects or withdrawal.
  • Weight loss or gain: Significant changes in appetite leading to weight loss or gain.
  • Neglect of personal grooming: Decreased interest in personal hygiene and grooming.
  • Drowsiness and fatigue: Feeling unusually tired, lethargic or drowsy as the body’s response to the drug’s effects.

Psychological signs of oxycodone addiction

  • Cravings: Experiencing strong urges or cravings to use oxycodone.
  • Loss of interest: Showing a lack of interest in activities or hobbies that were once enjoyed.
  • Mood swings: Experiencing rapid and extreme changes in mood, ranging from euphoria when using the drug to deep depression or irritability when not.
  • Anxiety and paranoia: Developing anxiety, paranoia or other mental health issues not present before oxycodone use.
  • Cognitive impairment: Experiencing difficulties with concentration, decision-making and memory.

Behavioural signs of oxycodone addiction

  • Doctor shopping: Visiting multiple doctors or pharmacies to obtain more oxycodone prescriptions. (This type of behaviour is observable in countries that have privatised healthcare systems, such as the US.)
  • Isolation: Withdrawing from family, friends and social activities.
  • Financial issues: Spending large amounts of money on oxycodone, leading to financial problems.
  • Legal problems: Encountering legal issues related to obtaining or using oxycodone, such as forging prescriptions or being arrested for possession.
  • Neglecting responsibilities: Failing to fulfil responsibilities at home, work or school due to drug use.

I’ve been prescribed oxycodone by my doctor; should I be worried?

Being prescribed oxycodone by your doctor suggests that your medical needs have been carefully considered. However, it’s natural to have concerns due to the known risks associated with opioid medications. Here’s how you can responsibly manage your oxycodone prescription:

  • Follow your doctor’s instructions precisely: This cannot be overstated. The dosage and frequency prescribed by your doctor are tailored to your specific situation. Do not adjust the dose independently, and ensure you know how long you should take the medication.
  • Regular check-ups: Your doctor may schedule regular appointments to monitor your response to the medication, adjust the treatment plan if necessary and check for any signs of side effects or dependency. These check-ups are crucial for safely managing your use of oxycodone.
  • Understand the risks: Educate yourself about the potential side effects and risks of oxycodone. Knowing these can help you recognise early signs of dependency or adverse reactions and seek timely help.
  • Alternative pain management strategies: Depending on your situation, your doctor might also recommend non-opioid pain relief strategies alongside oxycodone, such as physical therapy, exercise or certain non-opioid medications.

It’s very important to maintain open communication with your healthcare provider about your pain and any concerns you have regarding your medication. If you’re feeling anxious about taking oxycodone, discuss these feelings with your doctor.

How can I tell if I’m addicted to oxycodone?

Even when oxycodone is prescribed by a healthcare professional and taken as directed, it’s important to regularly check in on your usage and be mindful of how your body and mind are responding. Addiction can subtly take hold, altering your behaviour, health and relationships before you fully realise what’s happening.

If you’re concerned about your use of oxycodone, asking yourself the following questions can help determine if you might be developing an addiction.

  1. Do you find yourself taking more oxycodone than prescribed or taking doses more frequently than directed? Increasing dosage without a doctor’s guidance can be a sign of developing tolerance and dependence.
  2. Have you ever felt a compulsive urge to use oxycodone, even when you’re not in pain? Using oxycodone to feel good emotionally rather than to relieve physical pain can indicate addictive behaviour.
  3. Do you spend a significant amount of time thinking about oxycodone, including when you’ll take your next dose or how to obtain more? Preoccupation with the drug is a common sign of addiction.
  4. Have you tried to cut down or stop using oxycodone but found you couldn’t? Inability to quit despite wanting to is a hallmark of addiction.
  5. Do you experience withdrawal symptoms (like nausea, muscle aches, agitation or anxiety) when you haven’t taken oxycodone for a while? Withdrawal symptoms indicate key oxycodone addiction symptoms.
  6. Has your use of oxycodone negatively impacted your job, relationships or financial status? Addiction often leads to difficulties in managing daily life and responsibilities.

If you answered ‘yes’ to any of these questions, seeking professional help is important. This could be through the aforementioned check-ins with your doctor. They may suggest further help for addiction to oxycodone.

What are the treatment options for oxycodone addiction?

At Sanctuary Lodge, your journey to overcome addiction to oxycodone begins with a medically supervised detox stage, ensuring your safety and comfort while managing withdrawal symptoms. This initial phase is crucial for clearing your body of substances and setting a solid foundation for your recovery.

Following detox, you’ll move into the therapy stage, which includes a comprehensive blend of traditional and holistic approaches. This is designed to address both the psychological aspects of your addiction to oxycodone and your overall well-being. You’ll participate in Dialectical Behaviour Therapy (DBT), one-to-one counselling, and group therapy sessions. These are aimed at building self-awareness and developing coping strategies.

You’ll also experience holistic therapy options, like art therapy and yoga, integrated to promote your mental health and enhance physical wellness. We aim to offer you a well-rounded recovery experience by adding holistic methods to our programme.

Aftercare is a pivotal component of your journey, providing ongoing support through continued therapy sessions and resources to help you maintain sobriety. The main aim of our aftercare services is to support your reintegration into daily life outside our facility.

What’s next?

Take the first step towards reclaiming your life from oxycodone addiction with Sanctuary Lodge. Our expert-led inpatient rehab offers a comprehensive recovery journey, combining medical detox, personalised therapy and aftercare support. Embrace a holistic approach to healing with our traditional and innovative therapies, all within a supportive community. Don’t let your oxycodone addiction define you. Contact Sanctuary Lodge today and venture on a path to wellness and sobriety. Your journey to recovery starts here.

(Click here to see works cited)

  • Green, Katlyn, et al. “Prescribing Trends of Gabapentin, Pregabalin and oxycodone: A Secondary Analysis of Primary Care Prescribing Patterns in England.” BJGP Open, Royal College of General Practitioners, 1 Oct. 2019, bjgpopen.org/content/3/3/bjgpopen19X101662.
  • Remillard D, Kaye AD, McAnally H. oxycodone’s Unparalleled Addictive Potential: Is it Time for a Moratorium? Curr Pain Headache Rep. 2019 Feb 28;23(2):15. doi: 10.1007/s11916-019-0751-7. PMID: 30820686.
  • Sadiq NM, Dice TJ, Mead T. oxycodone. [Updated 2022 Aug 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482226/
  • Jayawant SS, Balkrishnan R. The controversy surrounding OxyContin abuse: issues and solutions. Ther Clin Risk Manag. 2005;1(2):77-82. doi:10.2147/tcrm.1.2.77.62911
  • Sapkota A, Takematsu M, Adewunmi V, Gupta C, Williams AR, Friedman BW. oxycodone induced euphoria in ED patients with acute musculoskeletal pain. A secondary analysis of data from a randomized trial. Am J Emerg Med. 2022 Mar;53:240-244. doi: 10.1016/j.ajem.2022.01.016. Epub 2022 Jan 13. PMID: 35085877.
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