Vicodin Addiction

Nicki Hari

Written by:

Nicki Hari

Last Updated:

April 10th, 2025

Opioids can be lethal if misused, underscoring the importance of educating oneself on their potentially destructive properties. One such opioid, hydrocodone, is found in painkillers such as Vicodin. This page aims to highlight the dangers of Vicodin addiction and how those in need can get help for their addiction.

What is Vicodin?

Vicodin is a prescription medication used to relieve moderate to moderately severe pain. It is a combination drug consisting of two primary ingredients: paracetamol and hydrocodone. Paracetamol is a pain reliever and a fever reducer that works by inhibiting the production of certain chemicals in the brain that cause pain and fever. Hydrocodone is a semi-synthetic opioid analgesic that works by binding to particular receptors in the brain and nervous system to decrease the perception of pain.

Vicodin is commonly prescribed for the relief of pain conditions that are not adequately managed by non-narcotic pain relievers. It can be used in cases of acute pain, such as pain following surgery or injury and sometimes for chronic pain under strict medical supervision. Due to its opioid content, Vicodin may also cause sedation and euphoria, which contributes to its potential for abuse.

Can you get Vicodin in the UK?

While Vicodin itself isn’t directly available for legal prescription in the UK, the individual components of the medication can still be obtained through legal channels.

In theory, a combination similar to Vicodin is conceivable within the UK through separate means. For example, those who are prescribed hydrocodone for pain management can, in theory, take paracetamol alongside it. Paracetamol is readily available over the counter in the UK and is legal to obtain without a prescription. This accessibility allows for the potential voluntary combination of the two substances by people seeking pain relief similar to what Vicodin offers.

It’s crucial to note, however, that any decision to combine medications should always be made under the guidance of a healthcare professional. This ensures the combination is safe and appropriate for the individual’s health needs. Healthcare providers can offer advice on dosages and timing to minimise the risk of adverse effects and ensure the efficacy of the pain management strategy.

Why does Vicodin have the potential to cause addiction?

Vicodin has a significant potential for addiction due to several factors inherent in how opioids affect the human body:

Neurochemical effects
Opioids like hydrocodone bind to specific receptors in the brain, spinal cord and other body parts. This binding action inhibits the transmission of pain signals to the brain, which is why Vicodin is effective at relieving pain. However, opioids also activate the brain’s reward system by increasing dopamine levels, a neurotransmitter associated with pleasure and satisfaction. This euphoria can potentially pave the way to Vicodin addiction.
Tolerance
With regular use over time, the body adapts to Vicodin, and higher doses are required to achieve the same pain-relieving effects. This can prompt people to take more than the prescribed amount to get relief from pain or to chase the euphoric feeling, increasing the risk of addiction.
Physical dependence
Prolonged use of Vicodin can lead to physical dependence, where the body adjusts to the drug’s presence and experiences withdrawal symptoms if the drug is reduced or stopped abruptly. These withdrawal symptoms can be uncomfortable and psychologically distressing, driving continued use of the medication to avoid these effects.

Withdrawal symptoms could include:

  • Nausea
  • Vomiting
  • Muscle aches and pains
  • Sweating
  • Diarrhoea
  • Runny nose
  • Sneezing
  • Anxiety
  • Irritability
  • Insomnia
  • Restlessness
  • Chills
  • Dilated pupils
  • Increased blood pressure
  • Increased heart rate
Psychological dependence
People may become psychologically dependent on Vicodin, using it to cope with stress or any underlying mental health issues, such as depression. The reliance on the drug for emotional well-being can make it difficult to stop using it, even when no longer needed for pain management.

What are the signs of Vicodin addiction?

Vicodin addiction can manifest through a range of physical, psychological and behavioural signs. It’s important to recognise these signs early to address the addiction effectively, either in yourself or in a loved one who’s taking Vicodin. Here’s how the signs of addiction can present across different aspects:

Physical signs

  • Tolerance: Needing larger doses of Vicodin to feel the same level of pain relief.
  • Withdrawal symptoms: Experiencing symptoms like sweating, shaking, nausea, vomiting, diarrhoea and muscle aches when not taking the drug.
  • Neglect of personal grooming: Showing less interest in hygiene or personal appearance.
  • Changes in sleep patterns: Experiencing insomnia or sleeping at odd hours.
  • Physical dependence: Experiencing physical withdrawal symptoms when not taking the drug indicates a physical dependence.

Psychological signs

  • Cravings: Experiencing strong desires or urges to use Vicodin.
  • Anxiety or depression: Feeling anxious, depressed or experiencing drastic mood swings unrelated to the pain Vicodin was prescribed for.
  • Preoccupation with the drug: Spending a lot of time thinking about Vicodin, including how to obtain more and when to take it next.
  • Decreased libido: Losing interest in sexual activity, which can be a side effect of long-term opioid use.

Behavioural signs

  • Doctor shopping: Visiting multiple doctors to obtain more Vicodin prescriptions.
  • Isolation from friends and family: Withdrawing from social activities and relationships that were once enjoyable.
  • Neglecting responsibilities: Failing to meet obligations at work, school or home due to drug use.
  • Illegal activities: Engaging in illegal activities, such as buying Vicodin on the black market or stealing to obtain the drug.
  • Using Vicodin despite negative consequences: Continuing to use Vicodin even when it causes problems with health, finances or relationships.

How do I know if I’m addicted to Vicodin?

When taking any form of medication that has the potential for addiction, it’s always worth checking in on yourself. This could be through discussing your relationship with Vicodin with your doctor or even taking the time to ask yourself a certain set of questions:

  1. Have you ever taken more Vicodin than you intended or taken it for a longer period than was prescribed?
  2. Do you often find yourself thinking about the next time you can take Vicodin or worrying about running out of it?
  3. Have you experienced uncomfortable physical or psychological symptoms when you’ve tried to stop taking Vicodin or when it wears off, such as nausea, irritability, sleep disturbances or anxiety?
  4. Has your use of Vicodin led to neglect of your family, work or educational responsibilities?
  5. Do you continue to use Vicodin even though it’s causing problems in your life, such as issues with relationships, health or financial difficulties?
  6. Have you found that you need to take more Vicodin to achieve the same effect you once had with lower doses or that the same amount has less effect than before?

Answering ‘yes’ to these questions can indicate patterns of use that may suggest a Vicodin addiction. Still, it’s crucial to consult with a healthcare professional for an accurate assessment and to discuss potential treatment options.

What can a Vicodin addiction do to your body?

Addiction to Vicodin can have widespread and serious consequences on a person’s health. These adverse effects could include:

  • Liver damage or failure: Extended use of Vicodin poses a significant risk to liver health because it contains paracetamol. High levels of paracetamol can exceed the liver’s processing capabilities, causing liver toxicity. This can escalate into severe liver damage or even life-threatening liver failure.
  • Respiratory problems: Hydrocodone can suppress the central nervous system, which oversees respiratory functions. This suppression can result in diminished, shallow breaths, lowering blood oxygen levels. Chronic use can lead to respiratory distress or failure, particularly if combined with other substances or during sleep.
  • Mental health complications: Long-term Vicodin use can trigger mental health problems, as the drug’s fleeting euphoria may worsen depression and anxiety symptoms upon fading. The ongoing battle with addiction can also heighten stress, anxiety and feelings of desolation.
  • Digestive system issues: Hydrocodone’s effect on slowing the digestive system can cause constipation and abdominal bloating. Persistent issues can lead to more conditions, such as bowel obstruction.

How can I get help for Vicodin addiction?

Seeking help for Vicodin addiction is a path best travelled with support. At Sanctuary Lodge, our dedicated professionals are with you at every step of your recovery process, aiding you in breaking free from the grip of Vicodin addiction. When you’re prepared to create a significant transformation in your life and pave the way to a Vicodin-free future, reach out to us.

(Click here to see works cited)

  • “Deaths Related to Drug Poisoning in England and Wales: 2022 Registrations.” Deaths Related to Drug Poisoning in England and Wales – Office for National Statistics, Office for National Statistics, 19 Dec. 2023, www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsrelatedtodrugpoisoninginenglandandwales/2022registrations.
  • Cofano S, Yellon R. Hydrocodone. [Updated 2023 Nov 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537288/
  • Kosten TR, George TP. The neurobiology of opioid dependence: implications for treatment. Sci Pract Perspect. 2002;1(1):13-20. doi:10.1151/spp021113
  • Habibi M, Kim PY. Hydrocodone and Acetaminophen. [Updated 2022 Dec 19]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538530/
  • LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Hydrocodone. [Updated 2020 Nov 24]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK548700/
  • Grunkemeier DM, Cassara JE, Dalton CB, Drossman DA. The narcotic bowel syndrome: clinical features, pathophysiology, and management. Clin Gastroenterol Hepatol. 2007;5(10):1126-1122. doi:10.1016/j.cgh.2007.06.013